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contact inhibition : ウィキペディア英語版 | contact inhibition
Normal somatic cells when grown in culture will become growth inhibited when they encounter another cell. 〔Klug, Cummings, et al. Concepts of Genetics. 10th ed. San Francisco. Pearson. 2012. Print.〕 The cells in our bodies are governed by ''growth control mechanisms'' and ''cellular senescence'' (aging). Cell aging puts a limit on the number of times a cell can divide: the more a cell has divided, the less likely it will be to divide again. Growth mechanisms are in place to stop or continue cell growth depending on the conditions.〔Dushek, Jennie, and Allen J. Tobin. Asking About Life. 1st ed. Belmont: Brooks/Cole-Thomson Learning, 2005. 161. eBook.〕 Contact inhibition is a growth mechanism. In most cases when two cells collide they attempt to move in a different direction to avoid future collisions. == Contact Inhibition of Growth ==
Contact inhibition is a growth mechanism which functions to keep cells growing into a layer one cell thick (a monolayer). If a cell has plenty of free space, it replicates rapidly and moves freely. This process keeps happening until the cells have divided so many times there is no longer any room in the layer for them to replicate. At this point, normal cells will stop replicating.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「contact inhibition」の詳細全文を読む
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